Publications

Insular epilepsy (IE) is an increasingly recognized cause of drug-resistant epilepsy amenable to surgery. However, concerns of suboptimal seizure control and permanent neurological morbidity hamper widespread adoption of surgery for IE. We performed a systematic review and individual participant data meta-analysis to determine the efficacy and safety profile of surgery for IE and identify predictors of outcomes.

Solli E, Colwell NA, Say I, Houston R, Johal AS, Pak J, Tomycz L. Deciphering the surgical treatment gap for drug-resistant epilepsy (DRE): A literature review. Epilepsia. 2020 Jul;61(7):1352-1364. doi: 10.1111/epi.16572. Epub 2020 Jun 19. PMID: 32558937.

Tomycz L, Hale AT, Abdulrazeq HF, Naftel RP, Englot DJ, Segal E. An algorithmic approach to preoperative studies and patient selection for hemispheric disconnection surgery: a literature review. Epileptic Disord. 2020 Oct 1;22(5):592-609. English. doi: 10.1684/epd.2020.1205. PMID: 33095169.

Laccheo I, Sonmezturk H, Bhatt AB, Tomycz L, Shi Y, Ringel M, DiCarlo G, Harris D, Barwise J, Abou-Khalil B, Haas KF. Non-convulsive status epilepticus and non-convulsive seizures in neurological ICU patients. Neurocrit Care. 2015 Apr;22(2):202-11. doi: 10.1007/s12028-014-0070-0. PMID: 25246236.

Tomycz LD, Hale AT, Haider AS, Clarke DF, Lee MR. Invasive Insular Sampling in Pediatric Epilepsy: A Single-Institution Experience. Oper Neurosurg (Hagerstown). 2018 Sep 1;15(3):310-317. doi: 10.1093/ons/opx253. PMID: 29244100.

Hale AT, Sen S, Haider AS, Perkins FF, Clarke DF, Lee MR, Tomycz LD. Open Resection versus Laser Interstitial Thermal Therapy for the Treatment of Pediatric Insular Epilepsy. Neurosurgery. 2019 Oct 1;85(4):E730-E736. doi: 10.1093/neuros/nyz094. PMID: 30888028; PMCID: PMC6748806.